Pancytopenia caused by iron-dextran.
نویسندگان
چکیده
منابع مشابه
Pancytopenia caused by iron-dextran.
Pancytopenia after intramuscular iron-dextran treatment occurred in an infant with Down's syndrome. Haematological abnormalities recurred on subsequent challenge. Positive migration inhibiting factor and mast cell degranulation tests support an allergic pathogenesis for the pancytopenia. These side effects have not been reported previously.
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Two hundred and fifty women with anaemia were treated by an infusion of iron-dextran and reviewed. No patient was considered for treatment by this method unless the haemoglobin concentration was less than 68.5% (10 g. on the scale 100%= 14.6 g./100 ml.). The first group consists of 50 patients with iron-deficiency anaemia in late pregnancy. The mean duration of pregnancy at the time of treatmen...
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Agranulocytosis and aplastic anaemia associated with sulphasalazine are well recognised, but pancytopenia caused by acute megaloblastic arrest of haemopoiesis while taking sulphasalazine has not previously been described. We report three patients who, after taking sulphasalazine for over two years, suddenly developed severe pancytopenia with gross megaloblastic changes in the marrow. In two pat...
متن کاملParenteral iron dextran therapy.
Parenteral iron therapy is indicated in patients with iron-deficiency anemia associated with conditions that interfere with the ingestion or absorption of oral iron. Replacement doses of iron required to replenish iron stores are based on body weight and the observed hemoglobin value. Methods of administering iron dextran are reviewed, including intramuscular and intravenous injections of the u...
متن کاملUtilization of iron dextran.
The utilization of iron dextran was investigated in normal subjects, in patients with iron-deficiency anaemia, and in anaemias associated with rheumatoid arthritis, reticulosis, and uraemia. Utilization of iron for haemoglobin formation at 14 days was found to be depressed in patients with rheumatoid arthritis, reticulosis, and uraemia, but when a concomitant iron-deficiency anaemia was present...
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ژورنال
عنوان ژورنال: Archives of Disease in Childhood
سال: 1986
ISSN: 0003-9888,1468-2044
DOI: 10.1136/adc.61.2.194